自己紹介

脳神経内科医として長年働いていますが,医師と患者間の知識のギャップによって生じる様々な問題を経験しています.このサイトは,その医療の常識のギャップを少しでも埋めるようなものになってくれればと考えています.

やりたいこと

市民の医療リテラシー向上と神経難病患者の支援活動。

趣味

コーヒー、ギター、サッカー、グルテンフリー料理

家族

妻と三人の息子と暮らしています。

経歴

  • 2000年3月 大阪朝鮮高級学校 卒業
  • 2001年4月 和歌山県立医科大学医学部 入学
  • 2007年4月 和歌山県立医科大学附属病院 研修医
  • 2009年4月 和歌山県立医科大学附属病院 神経内科 学内助教
  • 2010年4月 独立行政法人労働者健康福祉機構和歌山労災病院 神経内科 嘱託医
  • 2011年4月 和歌山県立医科大学附属病院 神経内科 学内助教
  • 2015年4月 和歌山県立医科大学附属病院 脳神経内科 助教
  • 2023年5月 和歌山県立医科大学附属病院 脳神経内科 講師
  • 2024年4月 和歌山県立医科大学附属病院 脳神経内科 博士研究員

資格

  • 総合内科専門医
  • 神経内科専門医・指導医
  • JMECCインストラクター

論文

1: Matsumoto T, Koh J, Sakata M, Nakayama Y, Yorozu S, Taruya J, Takahashi M, Miyamoto K, Ito H. Noise Pareidolia Test in Parkinson’s Disease and Atypical Parkinsonian Syndromes: A Retrospective Study. Cureus. 2024 Mar 3;16(3):e55436. doi: 10.7759/cureus.55436. PMID: 38567204; PMCID: PMC10986643.

2: Murakami K, Miyamoto K, Koh J, Kajimoto Y, Ito H. Three-year follow-up of rheumatoid meningitis with matrix metalloprotease-9 levels in the serum and cerebrospinal fluid as indicators of disease activity: A case report. J Neuroimmunol. 2024 May 15;390:578331. doi: 10.1016/j.jneuroim.2024.578331. Epub 2024 Mar 16. PMID: 38552529.

3: Sakata M, Miyamoto K, Koh J, Nagashima Y, Kondo T, Ito H. Japanese Mucuna pruriens (Hasshou beans) Showed Fast-acting and Long-lasting Effects in Parkinson’s Disease. Intern Med. 2024 Mar 11. doi:10.2169/internalmedicine.3171-23. Epub ahead of print. PMID: 38462520.

4: Tanaka R, Ota S, Taniguchi M, Koh J, Ito H, Murata S, Tanaka A. Recovery of cardiac metabolic function after high-dose prednisolone in a patient with inflammatory myopathy associated with anti-mitochondrial antibody. J Cardiol Cases. 2023 Nov 11;29(2):85-88. doi: 10.1016/j.jccase.2023.10.014. PMID: 38362584; PMCID: PMC10865124.

5: Takahashi M, Shimokawa T, Koh J, Takeshima T, Yamashita H, Kajimoto Y, Ito H. Effect of istradefylline on postural abnormalities in patients with Parkinson’s disease: An association study of baseline postural angle measurements with changes in Unified Dystonia Rating Scale total score. eNeurologicalSci. 2023 Dec 30;34:100493. doi: 10.1016/j.ensci.2023.100493. PMID: 38274039; PMCID: PMC10809095.

6: Ogami S, Koh J, Miyamoto K, Mori M, Takahashi M, Nakayama Y, Sakata M, Hiwatani Y, Kajimoto Y, Ishiguchi H, Ito H. Predictive value of the neutrophil-to-lymphocyte ratio for treatment response in patients diagnosed with definite or probable autoimmune encephalitis/encephalopathy. Front Neurol. 2023 Oct 23;14:1284717. doi: 10.3389/fneur.2023.1284717. PMID: 37936916; PMCID: PMC10626493.

7: Minamino M, Miyamoto K, Kuwahara M, Yoshikawa K, Koh J, Kusunoki S, Nagai Y, Ito H. Characteristics of Guillain-Barré syndrome in super-elderly individuals. J Neurol. 2023 Apr;270(4):2191-2196. doi: 10.1007/s00415-023-11567-8. Epub 2023 Jan 16. PMID: 36645487.

8: Yasui M, Koh J, Nakayama Y, Sakata M, Hiwatani Y, Ishiguchi H, Ito H. Diagnostic utility of susceptibility-weighted imaging in amyotrophic lateral sclerosis. J Neurol Sci. 2023 Jan 15;444:120524. doi: 10.1016/j.jns.2022.120524. Epub 2022 Dec 12. PMID: 36563605.

9: Tada Y, Kume K, Noguchi S, Sekiya T, Nishinaka K, Ishiguchi H, Koh J, Emori S, Nakayama Y, Kurashige T, Izumi Y, Ito H, Sakai N, Kawakami H. Correction: Comparison of two families with and without ataxia harboring novel variants in PRKCG. J Hum Genet. 2022 Oct;67(10):621. doi: 10.1038/s10038-022-01064-7. Erratum for: J Hum Genet. 2022 Oct;67(10):595-599. PMID: 35794208.

10: Kita A, Tsuji T, Koh J, Takahashi S, Yamamoto M, Sakamoto Y, Itogawa H, Kimoto S. Probable progressive supranuclear palsy in a patient with chronic schizophrenia: A case report. Exp Ther Med. 2022 Jun 1;24(1):484. doi: 10.3892/etm.2022.11411. PMID: 35761809; PMCID: PMC9214598.

11: Tada Y, Kume K, Noguchi S, Sekiya T, Nishinaka K, Ishiguchi H, Koh J, Emori S, Nakayama Y, Kurashige T, Izumi Y, Ito H, Sakai N, Kawakami H. Comparison of two families with and without ataxia harboring novel variants in PRKCG. J Hum Genet. 2022 Oct;67(10):595-599. doi: 10.1038/s10038-022-01057-6. Epub 2022 Jun 28. Erratum in: J Hum Genet. 2022 Jul 7;: PMID: 35760954.

12: Koh J, Takahashi M, Ohmae Y, Taruya J, Sakata M, Yasui M, Terada M, Ito H. A single-arm open-label pilot study of brief mindfulness meditation to control impulsivity in Parkinson’s disease. PLoS One. 2022 Apr 6;17(4):e0266354. doi: 10.1371/journal.pone.0266354. PMID: 35385563; PMCID: PMC8985985.

13: Takahashi M, Koh J, Yorozu S, Kajimoto Y, Nakayama Y, Sakata M, Yasui M, Hiwatani Y, Weintraub D, Ito H. Validation of the Japanese Version of the Questionnaire for Impulsive-Compulsive Disorders in Parkinson’s Disease-Rating Scale (QUIP-RS). Parkinsons Dis. 2022 Mar 23;2022:1503167. doi: 10.1155/2022/1503167. PMID: 35371432; PMCID: PMC8967585.

14: Miyamoto K, Koh J, Takahashi M, Niwa M, Ito H. A case of anti-MOG antibody-positive ADEM following COVID-19 mRNA vaccination. Neurol Sci. 2022 Jun;43(6):3513-3514. doi: 10.1007/s10072-022-06019-6. Epub 2022 Mar 19. PMID:35305170; PMCID: PMC8933853.

15: Yasuda K, Uenishi S, Sakamoto H, Hori K, Koh J, Takahashi S. Schizophrenia after remission of anti-NMDA receptor encephalitis. Asian J Psychiatr. 2022 Apr;70:103027. doi: 10.1016/j.ajp.2022.103027. Epub 2022 Feb 12. PMID: 35180463.

16: Takahashi M, Shimokawa T, Koh J, Takeshima T, Yamashita H, Kajimoto Y, Mori A, Ito H. Efficacy and safety of istradefylline in patients with Parkinson’s disease presenting with postural abnormalities: Results from a multicenter, prospective, and open-label exploratory study in Japan. J Neurol Sci. 2022 Jan 15;432:120078. doi: 10.1016/j.jns.2021.120078. Epub 2021 Dec 4. PMID: 34923334.

17: Murakami K, Koh J, Taruya J, Ito H. Neurosarcoidosis Mimicking the Recurrence of Malignant Lymphoma. Case Rep Neurol. 2021 Sep 14;13(3):605-612. doi: 10.1159/000518378. PMID: 34703450; PMCID: PMC8460933.

18: Koh J, Taruya J, Mori M, Ito H. Primary phlebitis of central nervous system revealed by black-blood magnetic resonance imaging. BMJ Case Rep. 2021 Oct 13;14(10):e245682. doi: 10.1136/bcr-2021-245682. PMID: 34645637; PMCID: PMC8515428.

19: Murakami K, Koh J, Takahashi M, Ito H. [Acute-onset autoimmune autonomic ganglionopathy remarkably effective in intravenous high-dose immunoglobulin therapy]. Rinsho Shinkeigaku. 2021 Oct 28;61(10):687-691. Japanese. doi: 10.5692/clinicalneurol.cn-001631. Epub 2021 Sep 25. PMID: 34565756.

20: Koh J, Takahashi M, Sakata M, Yasui M, Yorozu S, Ito H. Preventive effect of a heparinoid-containing product on the application site reaction of the rotigotine transdermal patch in Parkinson’s disease: A pilot randomized clinical trial (the SkinHeRo study). Clin Park Relat Disord. 2021 Aug 13;5:100105. doi: 10.1016/j.prdoa.2021.100105. PMID: 34458718; PMCID: PMC8379504.

21: Hosoi H, Tanigawa I, Kosako H, Okamoto A, Iwamoto R, Koh J, Mori M, Hiroi T, Mushino T, Murata S, Tamura S, Murata SI, Tomita A, Sonoki T. Liquid biopsies of plasma and cerebrospinal fluid are useful for detection of intravascular lymphoma with central nervous system symptoms alone. Ann Hematol. 2022 Mar;101(3):709-711. doi: 10.1007/s00277-021-04572-2. Epub 2021 Jul 3. PMID: 34216243.

22: Amato AA, Hanna MG, Machado PM, Badrising UA, Chinoy H, Benveniste O, Karanam AK, Wu M, Tankó LB, Schubert-Tennigkeit AA, Papanicolaou DA, Lloyd TE, Needham M, Liang C, Reardon KA, de Visser M, Ascherman DP, Barohn RJ, Dimachkie MM, Miller JAL, Kissel JT, Oskarsson B, Joyce NC, Van den Bergh P, Baets J, De Bleecker JL, Karam C, David WS, Mirabella M, Nations SP, Jung HH, Pegoraro E, Maggi L, Rodolico C, Filosto M, Shaibani AI, Sivakumar K, Goyal NA, Mori-Yoshimura M, Yamashita S, Suzuki N, Aoki M, Katsuno M, Morihata H, Murata K, Nodera H, Nishino I, Romano CD, Williams VSL, Vissing J, Zhang Auberson L; RESILIENT Study Extension Group. Efficacy and Safety of Bimagrumab in SporadicInclusion Body Myositis: Long-term Extension of RESILIENT. Neurology. 2021 Mar 23;96(12):e1595-e1607. doi: 10.1212/WNL.0000000000011626. Epub 2021 Feb 17. PMID: 33597289; PMCID: PMC8032371.

23: Koh J, Kaneoke Y, Donishi T, Ishida T, Sakata M, Hiwatani Y, Nakayama Y, Yasui M, Ishiguchi H, Hironishi M, Murata KY, Terada M, Ito H. Increased large-scale inter-network connectivity in relation to impulsivity in Parkinson’s disease. Sci Rep. 2020 Jul 10;10(1):11418. doi: 10.1038/s41598-020-68266-x. PMID: 32651411; PMCID: PMC7351767.

24: Horie R, Kubota T, Koh J, Tanaka R, Nakamura Y, Sasaki R, Ito H, Takahashi MP. EF hand-like motif mutations of Nav1.4 C-terminus cause myotonic syndrome by impairing fast inactivation. Muscle Nerve. 2020 Jun;61(6):808-814. doi: 10.1002/mus.26849. Epub 2020 Mar 17. PMID: 32129495.

25: Hosokawa M, Murata KY, Hironishi M, Koh J, Nishioka K, Nakao N, Ito H. Superficial siderosis associated with duplicated dura mater detected by CISS reverse MRI. J Neurol Sci. 2018 Sep 15;392:38-43. doi: 10.1016/j.jns.2018.07.001. Epub 2018 Jul 5. PMID: 30097152.

26: Maeki T, Tajima S, Kyaw AK, Matsumoto F, Miura K, Yamashita A, Yoshikawa A, Negishi K, Noguchi Y, Tadokoro K, Abe K, Taruya J, Koh J, Ito H, Ikegaya A, Abe F, Wada M, Nishigata T, Ikeda M, Kato F, Taniguchi S, Nakayama E, Takasaki T, Morita K, Lim CK, Saijo M. Comparison of Neutralizing Antibody Titers against Japanese Encephalitis Virus Genotype V Strain with Those against Genotype I and III Strains in the Sera of Japanese Encephalitis Patients in Japan in 2016. Jpn J Infect Dis. 2018 Sep 21;71(5):360-364. doi: 10.7883/yoken.JJID.2018.126. Epub 2018 Jun 29. PMID: 29962489.

27: Takeshima K, Ariyasu H, Ishibashi T, Kawai S, Uraki S, Koh J, Ito H, Akamizu T. Myotonic dystrophy type 1 with diabetes mellitus, mixed hypogonadism and adrenal insufficiency. Endocrinol Diabetes Metab Case Rep. 2018 Jan 18;2018:17-0143. doi: 10.1530/EDM-17-0143. PMID: 29367875; PMCID: PMC5777164.

28: Koh J, Ito H. Differential diagnosis of Parkinson’s disease and other neurodegenerative disorders. Nihon Rinsho. 2017 Jan;75(1):56-62. English, Japanese. PMID: 30566295.

29: Koh J, Yamamoto K, Sakata M, Murata KY and Ito H. Quantitative reference value of dopamine transporter single-photon emission computed tomography in healthy Japanese older adults. Neurology and Clinical Neuroscience. 19 June 2016. doi: 10.1111/ncn3.12082.

30: Nagashima Y, Kondo T, Sakata M, Koh J, Ito H. Effects of soybean ingestion on pharmacokinetics of levodopa and motor symptoms of Parkinson’s disease–In relation to the effects of Mucuna pruriens. J Neurol Sci. 2016 Feb 15;361:229-34. doi: 10.1016/j.jns.2016.01.005. Epub 2016 Jan 6. PMID: 26810548.

31: Miwa H, Koh J, Kajimoto Y, Kondo T. Effects of T-type calcium channel blockers on a parkinsonian tremor model in rats. Pharmacol Biochem Behav. 2011 Feb;97(4):656-9. doi: 10.1016/j.pbb.2010.11.014. Epub 2010 Nov 26. PMID: 21112351.